{"id":130777,"date":"2025-05-09T16:24:20","date_gmt":"2025-05-09T16:24:20","guid":{"rendered":"https:\/\/teknomers.com\/en\/low-dose-versus-high-dose-of-medicine-against-acne-and-acne-news-trondelag-local-news-tv-and-radio\/"},"modified":"2025-05-09T16:24:22","modified_gmt":"2025-05-09T16:24:22","slug":"low-dose-versus-high-dose-of-medicine-against-acne-and-acne-news-trondelag-local-news-tv-and-radio","status":"publish","type":"post","link":"https:\/\/teknomers.com\/en\/low-dose-versus-high-dose-of-medicine-against-acne-and-acne-news-trondelag-local-news-tv-and-radio\/","title":{"rendered":"Low dose versus high dose of medicine against acne and acne – news Tr\u00f8ndelag – local news, TV and radio"},"content":{"rendered":"\n

The case summarized the use of isotretinoin, a medicine against severe acne, has increased sharply in Norway in recent years. Many are reluctant to start because of potential side effects. A study from Harvard Medical School shows that a low dose of isotretinoin for a long time can produce the same results as a high dose, with less side effects. Isotretinoin is a chemical representation of vitamin A taken in tablet form over several months. It reduces sebum production, dampens the inflammation of the skin and changes the bacterial flora. The summary is made by a Ki service from Openai. The content is quality assured by news’s \u200b\u200bjournalists before publishing. Mina Emilie Opdal has long been plagued with deep pimples far down in the skin that created scar tissue. The pimples came in connection with the period, but could hardly disappear before the next while stood for a turn. Fortunately for her, there is a medicine against severe acne that works for most people. It has been a favorite of dermatologists since the 1980s. No new medicine has come out and thanked it. But for Opdal, it took a long time before she dared to give the medicine a chance. Mina Emilie Opdal (26) says that the skin problem went hard beyond the quality of life. Photo: Mina Emilie Opdal The mystery The drug is called isotretinoin, and is a chemical representation of vitamin A taken in tablet form over several months. – This one has been the rescue of hundreds of thousands of people, says dermatologist Michael Zangani. Last year, 32,500 Norwegians used this medicine. There are over 10,000 more than in 2020. Most who use it are between 15 and 24 years. There is something mysterious associated with isotretinoin. No one knows why it works so well against acne. Michael Zanganihar been a dermatologist for over 12 years. One of what he does most is to print isotretinoin and follow up patients who go on the medicine. What is certain, however, is what happens: sebum production is slowed down, the inflammation of the skin is dampened and the bacterial flora changes. – No other medication, laser or creams can be closer to the effect, says Zangani. There are long queues for help with acne: But even if you struggle both physically and mentally because of acne, many are scared from starting the medicine because of the side effects they are predicted. Like Mina Emilie Opdal. Dryness and muscle probe She had tried everything to overcome the skin problem. Used various prescription creams and antibiotic courses. Changed diet and dropped alcohol, among other things. Nothing had an effect. Three months after she first received the prescription on the strong medicine isotretinoin, she dared to go to the pharmacy. – I got rid of all summer to begin – had completely panic. I was terrified of the side effects I had heard so much about, especially the mental side effects, says Opdal. You’ve put her before, you think? Opdal works with Influens Sophie Elise, and has previously told about how she secured the dream job: At Tiktok, she constantly got videos from people who talked about deep depression in connection with drug use. – It is very rare for isotretinoin to cause deep depression, explains dermatologist Zangani, pointing to research in the field. Opdal misses a topic when talking about acne treatment: – The mental burden of having acne is too much worse than the side effects one gets from isotretinoin. She is supported by Zangani. – There is a high incidence of anxiety and depression in patients struggling with acne. Getting rid of it is of great help to them, he says. Mina Emilie Opdal stepped up relatively quickly to take three tablets with isotretinoin daily. Photo: Mina Emilie Opdal Opdal went on a high dose cure. During the cure, which took just over five months, she had very dry lips and dry nose, and pain in the muscles in connection with exercise. Everyone wants to get dry lips, Zangani states. Most people will also be dry in the skin and must be good at lubricating. Muscle and joint pain is common, and some experience dry eyes. New cure Mina Emilie Opdal got slowly but surely, a immaculate skin along the way. Mina Emilie Opdal started her second isotretinoin cure in January. Photo: Mina Emilie Opdal But then, a few months after she finished, the pimples returned. Not as bad as before, but still she chose five months ago to take another round with the medicine. Now, researchers from Harvard Medical School in the United States have stated that there is a way to take isotretinoin that does not cause strong side effects – combined with the risk of relapse not being affected. Low dose of almost 20,000 people participated in the study, published in Jama Dermatology. It shows that about 2 out of 10 that have been on isotretinoin gets pimples again a few years after they have completed the cure. The risk of relapse is greatest in women. In addition, the researchers found something they describe as interesting: Low dose gives exactly the same relapse risk as a high dose. Dermatologist John Barbieri, one of the researchers behind the Harvard study, says their findings are good news for many acne patients. -This provides the opportunity to create more individualized treatment regimens to achieve long-term fine skin and minimize side effects, Barbieri writes in an email from the United States. This means that each patient can be adapted to how much dose to take each day. John Barbierier dermatologist at Brigham and Women’s Hospital in Boston and a researcher at Harvard Medical School. Dermatologist Zangani says that low -dose of medicine was a trend a few years back, but that an important point was misunderstood. The misunderstanding – low dose is not a low dose over a short period of time. Unfortunately, it has some doctors without much experience with skin patients believed, says Zangani. The research from Harvard confirms that a low daily dose requires a long course of treatment. It is important to achieve the right total dose. The body weight determines how many pills with isotretinoin patients need to take to achieve the total dose. Photo: Sverre Lilleeng \/ news Mina Emilie Opdal now takes the medicine this way: Low daily dose over a long period of time. One tablet daily. – I have heard rumors that this is a good way to do it, and have talked to people I know who have got better results in this way, says Opdal. She is prepared to go on the tablets for a while. – Now the skin is terrific. There is very little that is so good as getting up in the morning and not being worried about what you encounter in the mirror. – When I got nice skin, I thought: Is it the way it really should be? Should life be so simple? Photo: Mina Emilie Opdal Many will be done quickly even if a low dose over a long period of time turns out to be a satisfactory alternative, Dermatologist Zangani believes most patients will still prefer to be finished as soon as possible. Many people think it is good to limit alcohol intake for a long time, which is recommended during the cure. Women should also not be pregnant while they are holding on. Also, everyone must regularly go to the doctor to take blood tests. – But if they get many ailments during a high dose cure, are afraid of side effects or feel they have time for it, it is perfectly fine to go on a lower dose – for a long time, says Zangani. Emilie lives with another skin disease that causes intense itching: Published 09.05.2025, at. 17.45
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The case summarized the use of isotretinoin, a medicine against severe acne, has increased sharply in Norway in recent years. Many are reluctant to start because of potential side effects. A study from Harvard Medical School shows that a low dose of isotretinoin for a long time can produce the same results as a high […]<\/p>\n","protected":false},"author":1,"featured_media":130778,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[2],"tags":[13522,2923,170,151,3583,16,152,62],"class_list":["post-130777","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-general","tag-acne","tag-dose","tag-high","tag-local","tag-medicine","tag-news","tag-radio","tag-trondelag"],"_links":{"self":[{"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/posts\/130777","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/comments?post=130777"}],"version-history":[{"count":0,"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/posts\/130777\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/media\/130778"}],"wp:attachment":[{"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/media?parent=130777"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/categories?post=130777"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/teknomers.com\/en\/wp-json\/wp\/v2\/tags?post=130777"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}