– I felt disgusting and horrible because I was so bloated. It could take three weeks between each time I got to go to the bathroom. I woke up at night with such big cramps in my stomach that I vomited. Marte Rykkje Halstensen from Stord had stomach pain for 28 years. It peaked in adolescence, and went hard beyond the self-image. She had irritable bowel syndrome (IBS). – I was quite young when I decided that I would be alone for the rest of my life. There was no one who had to be with someone like me, she says. But then she met a man who insisted that it should be them. In the late 20s, Halstensen struggled to have a surplus for both two young kids and a full-time job as a teacher. Irritable bowel syndrome (IBS) Irritable bowel syndrome (IBS) can cause ailments such as abdominal pain, constipation, bloating and diarrhea. People with irritable bowel syndrome can be very bothered, even though all routine examinations and tests show that there is no serious illness. The condition is common and around 10-12 out of 100 in the population is affected. Irritable bowel syndrome can affect both sexes and people of all ages, but the incidence is highest among women and young people. The cause of irritable bowel syndrome is unclear. There is no evidence that psychological factors such as depression, anxiety or hypochondria affect the occurrence or course of irritable bowel syndrome. On the other hand, it has been shown that stress can worsen symptoms. Stress management, proper diet and treatment can help reduce symptoms. Source: Norwegian Health Network Then came the rescue: Stool from a donor transplanted into the small intestine. – I was very bad the next day, and thought that this is going completely awry. But on day three I woke up and did not know my stomach. It was special, because I was used to always feeling pain, says. Now there is hope for more patients like Halstensen. TRASSA PAIN: – I worked full time when I was sick, but felt that I sacrificed the kids for it. I did not have enough surplus for them, says the 32-year-old. Photo: Eli Bjelland / news New data show long-term effect Through a tube in the throat, faeces from a healthy and well-trained person are passed down into the small intestine of the patient with irritable bowel. Characteristics of a super donor Between 30 and 40 years. Healthy and healthy, with normal BMI (weight to height ratio) Born vaginally and breastfeeding. Do not smoke and drink little alcohol. Do not use medication. Minimal antibiotic use is extra important. Preferably no antibiotics in the last year before donating stool. A lifestyle with exercise and a healthy diet. The treatment only takes ten minutes, but the effect can last for several years. It shows findings from a research project at Stord Hospital, in collaboration with Bergen Health and the University of Bergen. As many as nine out of ten patients improved their treatment after a short time. For about 75 percent of them, the effect of a dose lasts for at least three years, according to follow-up data, which was recently published in the internationally recognized journal “Gastroenterology”. VALUABLE POOP: Stool from a man in Stord has changed the lives of many patients with irritable bowel syndrome. Photo: Thomas Halleland / news Up to one million Norwegians have varying degrees of irritable bowel syndrome, but there is no effective treatment. Patients today are put on diets and painkillers and antidepressants. The results attract attention Fecal transplantation has been researched in several places, with varying results. The trial at Stord Hospital stands out as very promising. Researchers have also found eleven bacteria behind irritable bowel syndrome and fatigue. Nine of them should have a high level of. The other two we should have little of. MAGDY’S METHOD: Professor Magdy El-Salhy thinks he has found the factors that make research at Stord unique. Photo: Eli Bjelland / news – This opens up completely new possibilities for effective treatment. Imagine tablets or capsules that contain these nine bacteria, and that dissolve in the small intestine, says Magdy El-Salhy, chief physician and professor emeritus of gastroenterology. He believes that they have also found the optimal way to perform such transplants, and points to several factors: Factors for transplants: The donor has been selected according to strict conditions, and as far as we know is good and bad in terms of the bacterial flora. The donor went straight from the toilet to the freezer with the faeces. The bacteria do not tolerate exposure to air. Stools and sterile saline are mixed by hand before transplantation. Just like when you mix sugar in coffee or tea. In other experiments, a mixer has been used, but it breaks down the bacteria. The stool is transplanted to the small intestine. Others give it in the colon. Analyzes show that bacteria become vertebrae in the small intestine. In the large intestine, the bacterial flora changes only briefly, and returns in a short time. Does not receive money for further research He thinks fecal transplantation can be approved as treatment in just a couple of years. Then a large international study must first confirm the findings. – Research environment in several countries is ready, and the funding is in order. Patients are queuing to participate in the study. It’s just a matter of getting started, he says. But in Norway, research does not get money. The professional group has applied to Helse Vest and the Research Council for funding several times, but has been rejected. This year, they are applying to Helse Vest for the fifth time. FECES: In a refrigerator at Stord Hospital, there are several doses of feces from a man, who has contributed to the research for several years. Photo: Eli Bjelland / news – Irritable bowel syndrome is a major disease burden in society, and it is important to continue with this research. If we manage, for example, to produce a bacterial culture in a capsule that patients can swallow, it is a fantastic innovation, says Odd Helge Gilja. He is a section leader in the National competence service for gastroenterological ultrasound and chief physician in Helse Bergen, and professor at the University of Bergen. – We need more funding, either from Helse Vest, the Research Council or the EU, to start a larger international study. It requires quite large resources, says Gilja. UNIQUE RESEARCH: – The findings arouse international attention, and require further research, says Odd Helge Gilja, who contributed to the study. Photo: Jørgen Barth Helse Vest refers to previous answers about rejections of applications for research funding, which are distributed by the Regional Cooperation Body for Research and Innovation. “Many more applications than those that are awarded are considered eligible. It is first and foremost the financial framework that sets limits “, it is stated in the founding, among other things. Fears that the daughter will have to live with stomach ailments It has been almost four years since Marte Rykkje Halstensen woke up to a new life. She works as a teacher on the outdoor life line at Stord Folk High School. – It is a job I did not once dare to apply for if I was not healthy. Because I could not have had such a stomach on a trip for days. She hopes more people will now have access to fecal transplantation. The eight-year-old daughter has inherited her ailments, and she is restless. – If she’s going to have the youth I had, I’m very sorry. I live in the threat that when she gets big enough, they must have managed to fix this, she says. Marte Rykkje Halstensen got a new life without irritable bowel syndrome (IBS). Photo: Eli Bjelland / news
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Recovered from irritable bowel syndrome (IBS) by a dose of stool from super donor – news Vestland
